Let me start off with OOPS.
I recently migrated our databases/3rd party apps from SQL2008 on server 2008r2 to SQL2012sp4 on server 2016. Everything has been running smoothly until I did some clean up on the new 2016 server and found some event log errors:
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Failed to create AppDomain "master.sys[runtime].1237". Could not load file or assembly 'System.Data, Version=4.0.0.0, Culture=neutral, PublicKeyToken= or one of it's dependencies. Not enough storage is available to process this command.
I have plenty of space left on all the drives. The server has 20gb ram assigned to it, with only 11 being used - even with the max memory limit in the sql server itself being set to 16gb.
After doing some google'ing/research, I discovered that this issue is a result of having a 32bit SQL server installed and I thought, nah... there's no way that...