Antivirus is one of those necessary evils that we need to keep around, because if you don't implement it, you could be at risk. But if you do implement one, it can drive you insane. For example, if your antivirus happens to lock a SQL Server file before SQL Server can gain access to that file, potential issues could occur like not having access to these particular files or possible database corruption.
Luckily, Microsoft gives you someguidelines on how to handle implementing antiviruson your SQL Server and Pinal Dave has some bestpractices forfile exclusions, but what other approaches doy'all take? Do you even implement it at all?